Browse Items (9 total)

  • Tags: Fear Conditioning

Objective Pharmacologic and behavioral interventions that block reconsolidation of reactivated fear memory have demonstrated only limited success in modifying stronger and long-standing fear memories. Given the efficacy of Eye Movement…

Introduction: The inability to extinguish a conditioned fear is thought to be at the core of post-traumatic stress disorder. Eye movement desensitization and reprocessing therapy has been efficacious for post-traumatic stress disorder, but the brain…

Background and Objectives: It is assumed that fear responses can be altered by changing the contingency between a conditioned stimulus (CS) and an unconditioned stimulus (US), or by devaluing the present mental representation of the US. The aim of…

Disruption of fear conditioning, its extinction and its retrieval are at the core of Posttraumatic Stress Disorder (PTSD). Such deficits, especially fear extinction delay, disappear after Alternating Bilateral Stimulations (BLS) during Eye Movement…

Eye movement desensitization and reprocessing (EMDR) is seen as a promising treatment option for fear-related psychiatric diseases such as post-traumatic stress disorder (PTSD). Indeed, experimental studies have shown that performing goal-directed…

Posttraumatic stress disorder (PTSD) is a highly debilitating and prevalent psychological disorder. It is characterized by highly distressing intrusive trauma memories that are partly explained by fear conditioning. Despite efficient therapeutic…

Disruption of fear processing seems to be at the core of posttraumatic stress disorders (PTSD). Indeed, mechanisms of fear conditioning, extinction and extinction recall have been found to be disrupted in PTSD patients. We have demonstrated that such…

Although most people encounter at least one traumatic event over their lifetime, not all of them will develop post-traumatic stress disorder (PTSD). Lifetime prevalence of full-blown PTSD, known as an anxiety disorder, is in fact around 10%. In…

The article explores the differences between memory reconsolidation and extinction. This new area of investigation is worthy of additional attention. Reconsolidation may prove to be the underlying mechanism of EMDR, as opposed to extinction caused by…
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