3 controlled trials for PTSD: PE compared to 1) EMDR; 2) CPT; and 3) CR and CR + PE


3 CONTROLLED TRIALS FOR PTSD: PE COMPARED TO 1) EMDR; 2) CPT; AND 3) CR Chair: Barbara O. Rothbaum, Emory University School of Medicine, Psychiatry; Discussant: Terence M. Keane, Boston VA Medical Center Three randomized controlled trials treating PTSD in adult female rape victims will be presented: Patti Resick on long-term follow-up of Cognitive Processing Therapy (CPT) vs Prolonged Exposure (PE); Edna Foa on PE alone or with Cognitive Restructuring (CR); and Barbara Rothbaum on PE vs Eye Movement Desensitization and Reprocessing (EMDR) vs waitlist control.

PROLONGED EXPOSURE VS. EMDR FOR PTSD RAPE VICTIMS Barbara O. Rothbaum, Emory University School of Medicine, Psychiatry; Millie C. Astin, Emory University School of Medicine This controlled study aimed to evaluate the relative efficacy of Prolonged Exposure (PE) and Eye Movement Desensitization and Reprocessing (EMDR) compared to a notreatment wait-list control (WAIT) in the treatment of PTSD in adult female rape victims. In this study, 75 Ss with PTSD were randomly assigned to one of the three experimental conditions to achieve 20 completers per treatment group. All assessments were conducted by an Independent Assessor blind to the treatment condition, and standard measures of PTSD and related symptoms were incorporated. The primary goals of this study were to compare the relative efficacy of EMDR and PE, and compare them to the WAIT control group in treating PTSD in rape victims; to gather information on the differential rate of response to treatment; to develop predictors for response to treatment; and to gather information on the long-term response to treatment for six and twelve months following treatment. The mean age of participants was 34.3 (SD = 11.9) and ranges from 18-63 years. Most participants were Caucasian (69%); 24% are African American, 3% are Latino, and 3% are Other. The majority were single (53%), while 28% were married or living with a partner, and19% were divorced or separated. Treated patients were significantly more improved on all of the PTSD symptom categories as well as by PTSD diagnostic status than the WAIT participants immediately post-treatment. Means and standard deviations of PTSD symptom measures and other symptom measures will be presented and compared for participants who received PE, EMDR, and WAIT at Pre-Treatment and Post-Treatment and 6-month follow-up.

TWO-YEAR FOLLOW-UP OF A CLINICAL TRIAL COMPARING COGNITIVE PROCESSING THERAPY AND PROLONGED EXPOSURE FOR THE TREATMENT OF PTSD Patricia A. Resick, Pallavi Nishith, University of Missouri-St. Louis The purpose of this presentation will be to describe a telephone follow-up that was conducted two years after the completion of treatment in a controlled trial of cognitive behavioral treatments for PTSD. The treatment study compared cognitive processing therapy (CPT: Resick & Schnicke, 1992), prolonged exposure (PE: Foa et al. 1999) and a delayed treatment waiting-list condition (WL). Following the waiting period, participants in that condition were randomly assigned to one of the two therapy protocols. Participants were 171 female rape survivors who were randomly assigned to one of the three conditions. One hundred twenty-one women completed treatment and at least the post-treatment assessment. The initial study included three and nine month follow-ups. Although it had not been planned originally, we decided to add a two-year follow-up. As of 3/01, we have collected interview data and PTSD Symptom Scale scores (PSS) on 66 women who completed the following groups: CPT (21), PE (25), WL/CPT (9), and WL/PE (11). We have also collected two-year data on 21 women who dropped out after the first assessment, during treatment or after the waiting condition. Findings indicated that, after two years, the women who completed treatment continued to maintain the improvement they evidenced following therapy. There were no significant differences between the two types of treatment at the two-year follow-up although there was a trend for the DL/CPT group to have lower scores than the PE group. When the 66 treated women were collapsed and compared to the women who dropped out, there was no difference between the PSS scores of the two groups at pretreatment but a significant difference at the two-year follow-up, F(1,85)= 6.1, p






Edna B. Foa
Patricia Resick

Original Work Citation

Foa, E. B., & Resick, P. (2001, December). 3 controlled trials for PTSD: PE compared to 1) EMDR; 2) CPT; and 3) CR and CR + PE. Presentation at the the International Society for Traumatic Stress Studies 17th Annual Meeting, New Orleans, LA



“3 controlled trials for PTSD: PE compared to 1) EMDR; 2) CPT; and 3) CR and CR + PE,” Francine Shapiro Library, accessed October 26, 2020, https://emdria.omeka.net/items/show/21379.

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