EMDR therapy modulates the default mode network in a subsyndromal, traumatized bipolar patient

Description

Background: Some functional imaging abnormalities found in bipolar disorder are state related, whereas others persist into euthymia. It is uncertain to what extent these latter changes may reflect continuing subsyndromal affective fluctuations and whether those can be modulated by therapeutic interventions. Method: We report functional magnetic resonance imaging (fMRI) findings during performance of the n-back working memory task in a bipolar patient who showed a marked improvement in subsyndromal affective symptoms after receiving eye movement desensitization and reprocessing (EMDR) therapy in the context of a clinical trial. Results: The patient's clinical improvement was accompanied by marked changes in functional imaging, as compared to 30 healthy subjects. fMRI changes were noted particularly in deactivation, with failure of deactivation in the medial frontal cortex partially normalizing after treatment. Conclusions: This case supports the potential therapeutic overall benefit of EMDR in traumatized bipolar patients and suggests a possible neurobiological mechanism of action: normalization of default mode network dysfunction.
Copyright © 2013 S. Karger AG, Basel.

Format

Journal

Language

English

Author(s)

Ramon Landin-Romero
Patricia Novo
Victor Vicens
Peter J. McKenna
Antonia Santed
Edith Pomarol-Clotet
Pilar Salgado-Pineda
Francine Shapiro
Benedikt L. Amann

Original Work Citation

Landin-Romero, R., Novo, P., Vicens, V., McKenna, P. J., Santed, A., Pomarol-Clotet, E., Salgado-Pineda, P., Shapiro. F., & Amann, B. L. (2013, March). EMDR therapy modulates the default mode network in a subsyndromal, traumatized bipolar patient. Neuropsychobiology, 67(3), 181-184. doi:10.1159/000346654

Collection

Citation

“EMDR therapy modulates the default mode network in a subsyndromal, traumatized bipolar patient,” Francine Shapiro Library, accessed October 28, 2020, https://emdria.omeka.net/items/show/22045.

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