Psychological treatments for adults with posttraumatic stress disorder: A systematic review and meta-analysis

Description

Numerous guidelines have been developed over the past decade regarding treatments for Posttraumatic stress disorder (PTSD). However, given differences in guideline recommendations, some uncertainty exists regarding the selection of effective PTSD therapies. The current manuscript assessed the efficacy, comparative effectiveness, and adverse effects of psychological treatments for adults with PTSD. We searched MEDLINE, Cochrane Library, PILOTS, Embase, CINAHL, PsycINFO, and the Web of Science. Two reviewers independently selected trials. Two reviewers assessed risk of bias and graded strength of evidence (SOE). We included 64 trials; patients generally had severe PTSD. Evidence supports efficacy of exposure therapy (high SOE) including the manualized version Prolonged Exposure (PE); cognitive therapy (CT), cognitive processing therapy (CPT), cognitive behavioral therapy (CBT)-mixed therapies (moderate SOE); eye movement desensitization and reprocessing (EMDR) and narrative exposure therapy (low–moderate SOE). Effect sizes for reducing PTSD symptoms were large (e.g., Cohen's d ~− 1.0 or more compared with controls). Numbers needed to treat (NNTs) were < 4 to achieve loss of PTSD diagnosis for exposure therapy, CPT, CT, CBT-mixed, and EMDR. Several psychological treatments are effective for adults with PTSD. Head-to-head evidence was insufficient to determine these treatments' comparative effectiveness, and data regarding adverse events was absent from most studies.

Format

Journal

Language

English

Author(s)

Karen Cusack
Daniel E. Jonas
Catherine A. Forneris
Candi Wines
Jeffrey Sonis
Jennifer Cook Middleton
Cynthia Feltner
Kimberly A. Brownley
Kristine Rae Olmsted
Amy Greenblatt
Amy Weil
Bradley N. Gaynes

Original Work Citation

Cusack, K., Jonas, D. E., Forneris, C. A., Wines, C., Sonis, J., Middleton, J. C., . . . Gaynes, B. N. (2016, February). Psychological treatments for adults with posttraumatic stress disorder: A systematic review and meta-analysis. Clinical Psychology Review, 43, 128–141. doi:10.1016/j.cpr.2015.10.003

Collection

Citation

“Psychological treatments for adults with posttraumatic stress disorder: A systematic review and meta-analysis,” Francine Shapiro Library, accessed October 25, 2020, https://emdria.omeka.net/items/show/23581.

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