Overlapping frontoparietal networks in response to oculomotion and traumatic autobiographical memory retrieval: implications for eye movement desensitization and reprocessing

La sobreposición de redes fronto parietales en respuesta a los movimientos oculares y la recuperación de la memoria autobiográfica traumática: implicaciones para el reprocesamiento y desensibilización por movimientos oculares

负责眼动和创伤性自传记忆提取的额顶网络重叠:对眼动脱敏和再加工疗法的启示

Description

Background:
Oculomotor movements have been shown to aid in the retrieval of episodic memories, serving as sensory cues that engage frontoparietal brain regions to reconstruct visuospatial details of a memory. Frontoparietal brain regions not only are involved in oculomotion, but also mediate, in part, the retrieval of autobiographical episodic memories and assist in emotion regulation.

Objective:
We sought to investigate how oculomotion influences retrieval of traumatic memories by examining patterns of frontoparietal brain activation during autobiographical memory retrieval in post-traumatic stress disorder (PTSD) and in healthy controls.

Method:
Thirty-nine participants (controls, n = 19; PTSD, n = 20) recollected both neutral and traumatic/stressful autobiographical memories while cued simultaneously by horizontal and vertical oculomotor stimuli. The frontal (FEF) and supplementary (SEF) eye fields were used as seed regions for psychophysiological interaction analyses in SPM12.

Results:
As compared to controls, upon retrieval of a traumatic/stressful memory while also performing simultaneous horizontal eye movements, PTSD showed: i) increased SEF and FEF connectivity with the right dorsolateral prefrontal cortex, ii) increased SEF connectivity with the right dorsomedial prefrontal cortex, and iii) increased SEF connectivity with the right anterior insula. By contrast, as compared to PTSD, upon retrieval of a traumatic/stressful memory while also performing simultaneous horizontal eye movements, controls showed: i) increased FEF connectivity with the right posterior insula and ii) increased SEF connectivity with the precuneus.

Conclusions:
These findings provide a neurobiological account for how oculomotion may influence the frontoparietal cortical representation of traumatic memories. Implications for eye movement desensitization and reprocessing are discussed.

Format

Journal

Language

English

Author(s)

Sherain Harricharan
Margaret C. McKinnon
Mischa Tursich
Maria Densmore
Paul Frewen
Jean Théberge
Bessel van der Kolk
Ruth A. Lanius

Original Work Citation

Harricharan, S., McKinnon, M. C., Tursich, M., Densmore, M., Frewen, M., Théberge, J., van der Kolk, B., & Lanius, R. A. (2019). Overlapping frontoparietal networks in response to oculomotion and traumatic autobiographical memory retrieval: implications for eye movement desensitization and reprocessing. European Journal of Psychotraumatology, 10(1), 1586265. doi:10.1080/20008198.2019.1586265

Collection

Citation

“Overlapping frontoparietal networks in response to oculomotion and traumatic autobiographical memory retrieval: implications for eye movement desensitization and reprocessing La sobreposición de redes fronto parietales en respuesta a los movimientos oculares y la recuperación de la memoria autobiográfica traumática: implicaciones para el reprocesamiento y desensibilización por movimientos oculares 负责眼动和创伤性自传记忆提取的额顶网络重叠:对眼动脱敏和再加工疗法的启示,” Francine Shapiro Library, accessed May 28, 2020, https://emdria.omeka.net/items/show/25876.

Output Formats